Sentence examples for the main handicap from inspiring English sources

So, Cassidy says, "I think the main handicap [Romney] faced wasn't that he was a weak candidate — although he wasn't a great one — it was that he was representing the Republican Party, which is out of step with large portions of the country on a lot of issues".

The main handicap of the concentrating solar power technology is still the higher cost compared with the conventional coal power plant.

The main handicap of the busulfan treatment in rat models was the possibility of severe destruction of niche, especially Sertoli cells in testes.

The main handicap has been the lack of clinical trials, due largely to the comparative rarity of the disease and the rapidity of its progression.

This study, which set the focus on yeast key physiological parameters during the aerobic metabolism of synthetic must, concluded that high acetic acid yields constituted the main handicap for this application (Quirós et al. 2014).

These are the main handicaps for its large scale application in sodium ion batteries.

The incorporation of reinforcements with lower thermal stability than the matrix is one of the main handicaps of wood fibre composites.

Nevertheless, limited medical access, and conditions of water shortage were the main handicaps in reducing NTDs prevalence in these areas.

The main handicaps in assay performance were suboptimal sensitivity of in-house IgM detection protocols by comparison with better-performing commercial ELISA tests, and the presence of IgG cross-reactivity with heterologous flaviviruses.

However, its advantage is also its main handicap: high resolution allows the detection of a higher percentage of abnormalities than in a conventional karyotype but may also pick up unexpected findings and/or variants that are of unknown clinical significance [ 18].

Today, a main handicap with high throughput methods is the capacity for each individual research group to handle samples and data.