A large disparity in spectrum holdings may yield poor results with respect to both objectives, i.e. the lower cost-effectiveness of a larger number of MNOs, and the lower competitive pressure of a smaller number of MNOs.
Overall, the community and public health interventions tended to have high benefits and medium level overall costs and tended to have lower cost effectiveness ratios than many of the interventions in the other two categories.
Overall, community and public health interventions such as non-personal interventions for alcohol use, tobacco use, and cardiovascular risks tended to have lower cost effectiveness ratios than many clinical interventions (of varying complexity).
The probability of supported employment being cost-effective using the NICE lower cost-effectiveness threshold of £20,000/QALY is 67.1%, while at the NICE upper cost-effectiveness threshold of £30,000/QALY, it is 75.2%.
When analysis is restricted to interventions delivered from mainstream GP practices, it is more cost-effective (lower cost-effectiveness ratio) to deliver the intervention to the general Australian population rather than the Indigenous population (for the polypill, $11,000 compared to $13,000 DALY/saved).
As we incorporate clinical/empiric diagnosis of TB, adding a single diagnostic test to the overall diagnostic pathway results in a lower incremental benefit (and as shown in the supplement a lower cost-effectiveness).
Our results showed that increasing the use of extrafine formulations in these patients would have resulted in reduced expenditure, without simultaneous worsening of the health status in the treated population, because of the lower cost of these drugs, the effectiveness of which is equivalent to that of the other formulations.
Because the neonatal mortality rates reported in South Africa are much lower than the Indian study [ 32], one can expect lower cost-effectiveness from this intervention.
On the other hand, total annual costs of all screening tests in Finland have been estimated at 22.4 million euros, of which 78%% comprised of opportunistic screening services with significant over screening among some women and lower cost-effectiveness than that of the organized program [ 24, 25].
The single-tablet regimen resulted in better adherence, and therefore better quality of life as perceived by patients, corresponding to a €4541.00 lower cost-effectiveness ratio per QALY versus the multipill regimen, with a 17% lower cost in favor of the single-tablet regimen.
It may be that in a country where the threshold is high, a more expensive but effective drug is cost-effective, while this might not be the case for this same drug in a country with a lower cost-effectiveness threshold.
