The long-term phase was an open-label study in which the maximum LEV dose was administered for another 24 weeks.
In this study, we focus on the relationship between the long-term phase transformation and mechanical properties, which facilitates the simulation and prediction of properties under operating conditions.
Neuropsychological tests and the 31-item Quality of Life in Epilepsy (QOLIE-31) inventory were administered at baseline, at the end of the short-term phase, and at the end of the long-term phase.
In the long-term phase of an acid rock drainage (ARD) evolution profile, after any short-term neutralisation capacity provided by carbonate minerals is exhausted, the net acid release is a product of a declining acid generation rate (AGR) and a slower, long-term acid neutralisation rate mainly provided by gangue silicate minerals.
At the end of the long-term phase, these improvements were maintained, and both groups performed better in more areas, as measured by the Trail Making Test, WCST, and Delayed Visual Memory in the neuropsychological battery and the QOLIE-31 subscales Overall QOL and Health Status.
In the present study we also addressed the long-term phase, since chronic reactions may jeopardize the function of the electrode, and therefore the durability of the implant, in a number of ways.
Although it has been mentioned that NK cell numbers are significantly higher in rATG treated liver transplanted patients compared with antibody-free treated patients in the long-term phase [45], our data indicate a normalization of NK cell frequencies starting at day 11 posttransplantation (Figure 1).
Outcome measures were assessed at baseline, at the end of the short-term phase (12 weeks), at months 6, 9, 12 during the long-term phase and at the end of the long-term phase (15 months).
During the long-term phase of the trial SER responders received a continuous SER treatment as relapse prevention.
Data from SENSE were used to inform transition probabilities in the long-term phase of the model (years 2 5).
These issues impact individuals during the acute phase of diagnosis and treatment, but can evolve or persist in the long-term phase of survivorship 5, 6.
