Sentence examples for the locus of integration from inspiring English sources
Type II events often acquired 5' or 3' UTR portions from the locus of integration after the insertion.
However we cannot rule out the possibility that the superior performance of this promoter construct in A. gambiae is due to position effects associated with the sequence context at the locus of transgene integration in this line.
The main difficulties lie in the length of the GAA expansion needed to induce pathogenesis and the locus of genomic integration, as well as the intrinsic GAA instability that can result in contraction or elongation of the expansion.
The presence and the correct size of the resulting PCR product confirmed the correct locus of integration of the cassette.
Should such regulatory elements fortuitously be coopted at the genomic locus of integration, a functional retrogene might evolve (Brosius 1991).
We further examined the intimin subtype by sequencing the eae gene, the chromosome integration site of the locus of enterocyte effacement encoding the eae gene and a set of type III secretion system genes, and the presence and subtype of the cdtB gene as described (5 ).
D. Schematic for double homologous recombination of linearized pBS-DHFR-PbRON12 into Pbron12 locus causing disruption of the locus by integration of the selectable marker TgDHFR-TS.
However, we did not investigate the exact locus of gene integration for the single strains in more detail.
Since the same defined surface was used for all signals in the nucleus, the comparison of integration loci with control loci is not affected by the blurred surface.
For example, the mouse Prdm3 gene was firstly identified as a common locus of retroviral integration in myeloid leukemia and thereby name as ecotropic viral integration site 1 (evi1) [79].
To visualize microtubules, CFP-Atb2 or mCherry-Atb2 were expressed from the nmt81 promoter in the pREP81 plasmid (LEU2+), or mCherry-Atb2 was expressed from the endogenous locus by integration of the nmt41 promoter and the mCherry-coding region upstream of the atb2+ ORF.
