The reduction to five strategically located samples within the 65 ha fields reduces sampling efforts by up to ∼90% as compared to the common practice of soil grid sampling every 1 ha.
During the fieldwork, locating sample members was facilitated by having access to other family members from whom the field team could gather information.
The first consideration is the ability to accurately locate sample plots using handheld GPS units.
We investigate the potential benefits of locating sample points on an spatial rather than temporal basis.
Of the original 925 included subjects in the cohort, we could not locate samples in the biobank for 60 subjects, and 220 had insufficient volume for PFOS measurements.
By locating samples in the probabilistic most probable region, only a small number of samples are used to build a precise surrogate model in the end, and only a few actual limit state function evaluations are required correspondingly.
And although the samples from this nested sparse sampling are sparsely and non-uniformly located, the samples of the autocorrelation can be computed at any specified rate.
There are only a few polymorphisms which do not contribute to the discrimination of the samples, located at the center of the plot (point 0/0) or along a line that extends above or below this point.
For small samples located in the sample hole of the gasket the probe reveals sensitivity that is only ∼3 times less than that yielded by regular ESR cavities.
Using a long working distance objective (20× Nikon, NA = 0.35, WD = 22 mm), unpolarised light from a halogen lamp was focused into the sample located inside the chamber.
