Taking advantage of the genotypic information generated in that genome scan and the linkage maps built for the Churra sheep population, we performed a QTL analysis for the four traits related to parasite resistance considered in this experiment.
Compared to a similar set of maps constructed with a well-performing locus-ordering algorithm (RECORD) [ 26], the linkage groups built with JoinMap at the preset default settings of the program were inflated by 70±76%6%.
A genome-wide classical QTL scan was performed using the linkage maps built in our material in a previous study [ 28] and 8,417 SNPs evenly mapped across the 18 autosomes with the mean distances reported in Fernández et al. [ 39].
The linkage maps built via the conventional method, which typically means microsatellites are among the earliest to be added to the map, were longer than the equivalent maps that were constructed by adding microsatellites to the SNP maps (Tgu1 11.8 cM longer, Tgu1A 0.9 cM longer, Tgu2 10.2 cM longer, Tgu9 1.0 cM longer).
This paper shows how to determine the singular foci of planar linkages built with rotational links.
The linkage map was built using MAPMAKER 3.0b [ 69].
Marker order and genetic distances of the autosomic linkage map built for this commercial population were in accordance with the published ovine linkage map.
The consensus linkage map built with these data covers 136.2 cM with a mean inter-locus distance of 5 cM.
Funding for the data linkage to the built environment data was provided by Cancer Care Ontario and the Canadian Heart Health Surveys Longitudinal Follow-up Study Awardedry and PilotoProject (Awarded to S. Leatherdale and E. Hobin).
We used the OWB population as a mapping resource in order to directly compare RAD and EST-based SNP maps and to assess the quality and utility of a linkage map built with the two types of data.
