This is hard to accept, even if this figure might be overestimated because some of the most recent applications could become successful after the limiting date chosen for the analysis.
In both OS and PFS analyses, observation times were censored at the limit date of 30 September 2009 for patients in whom no event occurred.
The review was conducted on July 10, 2006, setting the defined PubMed limits "dates: published in the last 2 years" and "languages: German".
We searched PubMed to identify publications for inclusion, imposing the following limits: date, RCTs, human studies, English language and peer-reviewed.
The following search term was entered into pubmed: "hypertens* AND (complia* OR adhere* OR persiste*) AND (cost* OR econo*)" with the limits: "Publication Date from 1995/01/01, Humans, English".
The Federal Aviation Regulations governing airline pilot flight and duty-time limits date back to the 1930's.
Sediments deposited over this time have the advantage of being within the limits of radiocarbon dating, as well as being suitable for dating by other chronological methods (e.g., δ 18O dating, tephra chronology, and varve counting).
Thus, we modified the queries to first generalize some of the keyword matchings, and then removed the limits on publication type, dates, and so on.
Now limit the dates to the period you are interested in and specify the correct language.
The limits applied were: publication date from January 1990 to June 2010, species (human) and publication type (excluding editorials, letters and reviews).
