Sentence examples for the limited activity from inspiring English sources

Overall, however, our report indicates that the limited activity and the significant toxicity of DES should limit its use in patients who have previously progressed on AA and docetaxel, and that patients should be offered agents with a proven survival benefit or clinical trials in this situation.

Resistance to chemotherapy and multi-step carcinogenesis that limits the efficacy of targeted compounds are probably the leading causes of the limited activity of anticancer strategies in CRC.

Among the reasons for the limited activity are the high costs of land and construction and the added expenses of marketing to small users, industry professionals said.

However, the limited activity, toxicity and the development of resistance raised the current need for new potent nontoxic antiestrogen.

However, the limited activity of ceftazidime against Gram-positive bacteria is of concern in high-risk neutropenic patients, because streptococcal bacteremia is associated with high complication rates [27].

Although 68Ga-labeled PSMA ligands in particular 68Ga-PSMA-11 are 68Ga-PSMA-11 are 68Ga-PSMA-11 areicsuccessfullyisputablemployedhe hinh costheor a 68Ge/68Ga generator is a disadvantage when clinicsritg the lisindisputabley that can be eluthe daily.

As a result, despite the relatively limited activity, those funds that invested during the adverse market conditions delivered attractive returns to investors.

Imatinib was evaluated in several clinical trials, with the drug showing limited activity in the monotherapy of adult GBM [ 48, 49].

Third, against the background of the safe and also limited activity of the TRAIL death receptor-targeting reagents currently under clinical investigation (see introduction), it appears possible that cell surface-anchoring TRAIL variants with high-specific activity cause unanticipated side effects on nontransformed cells not recognized so far.

Differences in societal costs (medication, other (health) care and productivity) will be compared to differences in the number of limited activity days and in quality adjusted life years (Dutch EQ5D, SF6D, e-TTO, VAS).

The 2010 off-season proved limited activity on the Avs' part.