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As it stands, there are no common variants that account for a substantial portion of the liability to develop this disease [17].
It is thought that many genes of small effect contribute to the liability to develop BD.
Disturbances in the emotional dimension of approach versus withdrawal have a key role in the liability to develop psychopathology such as depression and anxiety disorders [ 24, 25], with which the FA has indeed been found to be associated [ 2, 26, 27].
In this study, transcript levels of muscle at slaughter were correlated with drip loss at post mortem meat stage in order to reveal insight into the biological processes that are initiated during life and thus are under genetic control and finally determine the liability to develop elevated drip loss.
Holistic expression profiling was integrated with QTL analysis for the trait of interest and for gene expression levels for creation of a priority list of genes out of the orchestra of genes of biological networks relevant to the liability to develop elevated drip loss.
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Irv and Jerry boldly proposed an alternative polygenic model, derived from the work of the Edinburgh mathematical geneticist DS (Douglas) Falconer, in which liability to develop schizophrenia has a normal "bell-shaped" distribution in the population (like height or weight) contributed to by many genes.
Schizotypy is a set of personality traits that convey liability to develop schizophrenia.
This might explain their liability to develop hepatic glycogenosis.
Vulnerability markers are supposed to represent proximately and specifically an underlying pathology linked to an increased liability to develop a complex disease.
The fact that oncocytic tumours can be both multiple and familial strongly suggests that there is a germline mutation conferring an increased liability to develop this type of thyroid tumour.
Identifying and promoting favorable early rearing conditions is one such approach in preventing or reducing the vulnerability or liability to developing mental disorders.
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