Yet, p-values cannot cancel out each other; the more significant spot has higher influence and the less significant one has a minor, yet still increasing effect on the overall significance.
To allow for an unbiased comparison, we obtained a second, strict set of CpGcluster islands simply by increasing the required statistical significance to p-value ≤ 1E-20 (i.e. filtering out the less significant islands), then obtaining a total 25,454 CGIs.
One of the less significant current contractions in journalism, you may think, and not universally mourned.
Lumping violations together tends to trivialize the most hazardous and gives the less significant more attention than they deserve, critics say.
Living.com's was the less significant of the two bankruptcy filings because selling furniture over the Internet is an experiment that many feel will not pan out soon.
Only 34 days are guaranteed airtime on the main ITV channel, however, with about 60 days due to be relegated to the less significant ITV4.
The less significant roads would receive no repairs at all, and ultimately reverted to humpbacked mud tracks or streams.
(In the interest of full disclosure, I note that one of the less significant chapters in that history is the two years I spent at Columbia in the late 1970s as a publicist).
Chess followed the pattern of the less significant labels but there was an extraordinary difference: Chess had at its disposal not just one or two musicians but the whole musical scene that had resulted from the development of rural Southern blues into the tough blues of the South Side of Chicago.
He has chosen to note briskly the less significant popes and to concentrate attention on the popes (John XXIII and Gregory the Great, for instance), the schisms (notably the Reformation and the break with Constantinople) and the events (including the Crusades and the struggle against atheistic communism) that have had most influence on the church and the world.
Chess followed the pattern of the less significant labels — but there was an extraordinary difference: Chess had at its disposal not just one or two musicians but the whole musical scene that had resulted from the development of rural Southern blues into the tough blues of the South Side of Chicago.
