Exact(1)
However, the first hypothesis seems more likely given that the associations in our study were significant, especially during the later trimester, in which the immune system in particular develops, but more study, for example, of the mechanism or development of other atopic conditions in relation to acid-suppressive drug use, is now warranted.
Similar(59)
4– 7 These sequelae are found more frequently in infants infected during the first trimester, a critical period for cerebral corticogenesis, 8 than in those infected during the later trimesters.
We reviewed the hospital charts of the patients, consisting of both information gathered in hospital as well as the care providers' office charts which are faxed to the hospital typically in the later third trimester.
Furthermore, because of field issues (e.g., rescheduled appointments), some participants may be seen during a later trimester but their visit recorded as occurring within the previous time window.
In addition, we classified women as either being in the first trimester of pregnancy (≤91 days) on 11 September or being in a later trimester, based on their gestational age at delivery.
The effects of pollutants on premature births in the later two trimesters were weak.
Similar associations were seen for each trimester, with a trend towards increasingly strong associations with later trimesters, although, in the adjusted models, significant associations were not seen for either birth weight variable in the first trimester or for standardized birth weight in the third trimester.
We believe that this abnormal association may represent adaptation to the high metabolic demands of pregnancy and future studies during later trimesters planned for these women are expected to provide better explanation.
The FDA has listed magnesium chloride as pregnancy category A, which means "Adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of a risk in later trimesters)" [ 99].
Mutations in placental mtDNA may occur in early pregnancy, leading to an onset of mitochondrial dysfunction in later trimesters.
Integrated care led to significant screening in first and second trimester, although we acknowledge that we should also have introduced a retesting strategy for later trimesters.
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