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A specific prediction of our detailed cis-regulatory analysis of the Strongylocentrotus purpuratus (Sp) endo16 gene was that the later expression of this gene would be driven by a midgut-specific transcriptional regulator.
Without exogenous T3 added to the system, a striking ventralized pattern emerged that resembled both early Dio2 RNA expression, as well as the later expression of the rod gene, rhodopsin [71] (Fig. 6A-A').
Early lung expression of TNF-α, IL-12, and chemokines was TLR4 dependent, while IFN-γ production and the later expression of TNF-α and IL-12 was dependent on TLR9.
This result prompts the expectation that the elevated androgens of Nazca boobies before siblicide, compared to blue-footed boobies (Fig. 1) and probably most other birds, also lead to the later expression of NAV behavior.
The products of these early expressed protease genes may well be contributing to penetration of prey membranes rather than extensive cytoplasmic hydrolysis, although the endonucleases are predicted to be exported so are likely to be involved in early breakdown of the prey DNA, before the later expression and action of exonucleases.
It acts in the immediate antiviral response and helps regulate the later expression of several IFNA [ 17].
Similar(46)
The most important point in the pathogenesis of fibrin ogen)olysis at an early stage of trauma is that there is a several hour time difference between the immediate t-PA release from the endothelium and later expression of PAI-1 mRNA, leading to an extreme imbalance of these molecules [ 81- 83].
For instance, in the wing disc, early expression is responsible for specifying the wing primordium whereas later expression sets up the D/V axis of the wing [ 8, 9].
However, early expression of otog marked two broad domains at the OV poles; later, expression appeared in a region of ventral epithelium between them (Fig. 2F-G′).
Conversely, AK080047 is expressed in a region consistent with the primary heart field at E7.5, with later expression in the linear heart tube at E8.5 and throughout the heart entire heart at E9.5.
The transcription factors tested were specifically picked for their later expression in the NSM just prior to the homing ability, so that early specification events would not be perturbed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com