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Another explanation is that MN frequencies in MONO are thought to provide an estimate of genomic instability accumulated over many years in stem cells and circulating T lymphocytes, whereas MN in BN provide a measure of the lesions that have accumulated in the DNA or in key proteins since the lymphocytes last replicated in vivo (Kirsch-Volders and Fenech 2001; Kirsch-Volders et al. 2011).

Furthermore, while our first replicate group was tested after the wild-caught birds had been in captivity for 1 month, the last replicate group was tested almost 3 months later yet we did not observe any tendency of replicate group(s) tested later to show less fear response.

The sequence composition of the chromosome imparts directional cues to FtsK to ensure that DNA is pumped in the appropriate direction (Bigot et al, 2005, 2007; Lesterlin et al, 2008), and the Ter sites ensure that dif remains in the last replicating region of the chromosome (Duggin et al, 2008b).

In bacteria, dif is located within the last-replicated region of the chromosome, ∼180° across from the origin of replication.

During chromosomal segregation the two origins are pulled to either pole, and the two termination regions remain near the cell center, where they are the last to be replicated and separated.

For the first two replicate days both groups were collected together from two colonies, while another two colony sources were used for the last two replicate days.

For individuals with records, trait Y, expressed in kg, was simulated as follows: (5) y ij = b mi + a m ij + exp ((b vi + a v ij ) / 2 ) ϵ ij, where b mi is the fixed effect simulated for the ith CG, amij is the breeding value of animal j for the mean of Y and the last term replicates random residual effects according to the exponential model described by SanCristóbal-Gaudy et al. [ 1].

In the last section we replicate the analysis by using 478 genomes from the Personal Genome Project [ 24].

The active copy of the X chromosome is replicated alongside the other autosomes, depending on its gene content, but the inactive copy is the last chromosome to be replicated in the S phase [2].

"Those cities that have struggled over the last 100 years have replicated their economies," the report authors said.

Fold change was calculated by taking the ratio between the average non-logged ratio for the last four samples (replicates included) taken in the growth curve to the average of the first four samples taken in the growth curve.

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