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The largest change was because of an annual event.
The Alexa Fluor FRET pair demonstrated the largest change in fluorescence, resulting in a 35% change.
The largest change in the core took place between ca. 5500 and 4200 cal.
In TSC, the largest change in FA was related to a comorbid diagnosis of ASD.
But possibly the largest change is the way that these events are reported.
Brexit requires the largest change to Britain's constitutional and legal framework ever undertaken.
3-D printing promises to be the largest change in production methods since the Industrial Revolution.
By far the largest change we've made is to introduce an action bar.
The Senate just approved the largest change to the U.S. tax code in 30 years.
The largest change in water supply reliability would occur in Miami (+22%) and Los Angeles (−17.9%), respectively.
The largest change in temperature was found in the last two decades, with a decadal increase of about 1 °C.
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CEO of Professional Science Editing for Scientists @ prosciediting.com