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In the present study, we have not included any non-genetic measured covariate effects in the model, since there were no measurements available for the large reference data.
The large reference sample allowed for the calculation of reference data for five-year age groups across a wide range of ages.
In 2002, the calibration cage was changed from the large reference box Leiden to the Carbon box Leiden.
Another strength is the large reference group for the SF-36 recruited from the same general population during 2006.
Gains in reliability were high in general, due to the large reference population, except for fertility and calving traits.
Due to the small size of both sets compared to the large reference set, p-values could not be corrected for multiple testing.
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Although percentages of disagreements were low for most comparisons (1 6%) there were many discrepancies between the large references sets (11%, 9%, 8% between dataset PL0 and datasets AL0, AL1, and AL2, respectively, Figure 1b).
It is arguably the largest reference work ever published in English (just beating the Oxford English Dictionary in length).
The larger reference group was selected by emailing staff members of the Public Health Foundation of India and personal networks of authors which included scientists, students, and lay people.
Pplacer and RAxML particularly capitalize on the larger reference databases to reduce error.
Although our center is the largest reference center in the country, the potential selection bias associated with this limitation should be taken into consideration when extrapolating our results.
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CEO of Professional Science Editing for Scientists @ prosciediting.com