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However, large scale protein quantification remains challenging, in particular due to the large expression range and proteome complexity [19] [21].
The more modest differences between adult and neonatal effector cells were masked by the large expression differences in naive cells.
It was also chosen for qRT PCR verification because of the large expression difference found between melanocyte and melanoma cell lines (see later).
While the large expression datasets were highly correlated (e.g., "Genetic Modification" and "Organism Part, R = 0.81), they were much less correlated with the high-resolution data (e.g., "Root Cells" and "Genetic Modification", R = 0.30).
This intermediate expression could make it more difficult to detect expression differences, while the large expression level changes in the NV-C severe group make it easy to detect them against NV-NC control.
The large expression due to lactation indicated a role of this AAT in milk synthesis and probably in the regulation of mTOR signaling through import of AA into cells and secretion into the cytoplasm of AA from endosomes (ie, intracellular regulation or buffering of mTOR).
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In post-natal ontogeny [Weickert et al., 2009] the PCDH11XY gene pair has the largest expression among the earliest expressed sexually dimorphic genes in the human brain.
In our predicted path, SMAD4 had the largest expression value as well as the highest negative correlation −0.696476 with differential expressed OCIAD2 among SMADs families.
As the figure showed, SMAD4 had the largest expression value as well as the highest negative correlation −0.696476 with differential expressed OCIAD2 among SMADs, followed by SMAD2 with correlation value −0.595238 and SMAD6 −0.571429.
His excesses, on and off the field, seemed really just the largest expression of his appetite for life.
It's not really an English thing, but he's kind of American in terms of the force and not needing permission to take his ideas to the largest expression".
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