Sentence examples for the key modification from inspiring English sources

Therefore, the key modification made in the linezolid structure was the replacement of morpholine moiety with its bioisostere, 2-oxa-6-azaspiro[3.3]heptane.

However, in this study, the phosphorylation of FoxO1 may not be the key modification for ERK1/2-mediated FoxO1 degradation.

However, DNA methylation was the key modification that accompanied the formation of an inaccessible chromatin structure and more stable gene silencing upon cellular activation and through cell division.

The key modification in the setup was that, the MZI clock signal was not directly sent to the A/D card as usual.

The key modification relates to the chromatographic purification of the ovine Fab fragments, where an affinity chromatography step has been replaced with sequential anion and cation exchange steps.

The key modification was that by choosing restriction enzymes that generated blunt ends fragments rather than ones with staggered ends, the custom enzyme-specific adaptors used in the original protocol [ 18] could be replaced with standard Illumina Y-adaptors.

The key modifications introduced in the new design are the use of a change of coordinates and a partial linearization that transform the system into a cascade form, to which an adaptive energy-shaping controller is applied.

Glycosylation is one of the key modifications in the secondary metabolite biosynthesis and is catalyzed by carbohydrate active enzymes (CAZymes) which include the superfamily of glycosyltransferases (GTs) [ 21].

The key modifications are avoiding the use of Spin-X filter columns during immunoprecipitation (IP) wash steps, including an RNase treatment following the IP, and collecting reference material after the IP rather the traditional "input" starting chromatin.

The key modifications concern: (i) use of novel statistical criteria for deriving a high-quality PG from experimental data; (ii) the application of local TR which allows only short paths to explain (and remove) a given edge; and (iii) a novel strategy to rank the edges with respect to their confidence.

The new key modification that allows observing oscillations of the current at room temperature is adding 55% of gallium in the barriers.