Sentence examples for the key controllers of from inspiring English sources
The NF-κB and Akt regulators, the key controllers of the pathways showing early activation/late repression expression mode (i.e. inflammation, immune response, cell proliferation and cell differentiation), have been previously reported to act synergistically [56] [59].
Transcriptional network analysis identifies NF-κB, NEMO, Akt, PPARγ and SREBP1 as the key controllers of these processes and suggests that direct regulatory interactions between these factors may govern the transition from early (stressed, inflammatory) to late (pathological, steatotic) hepatic adaptation to HF feeding.
This synchronous swap of the major functional signatures between the early and the late phase and the fact that the key controllers of the reciprocally regulated processes (as revealed by the network analysis (Figure 4, Figure 5)) are implicated in the mutual repression suggest that the regulatory exchange may occur via tightly controlled reactions, limited to few master regulators.
Polycomb groups are correlated with transcriptional repression of Nanog, Oct4, and Sox2 which are the key controllers of Human ES cell pluripotency.
The calcium-sensing receptor is the key controller of extracellular calcium homeostasis via its effects on regulation of parathyroid hormone secretion and renal calcium reabsorption [ 38].
Owing to the importance of the EBF class of genes as key controllers of the ethylene signal transduction pathway, this study used the apple genome sequence to identify EBF-like genes.
Epithelial cells may be key controllers of the inflammatory response to LPS in the airways.
Solid evidence now strongly supports the existence of the once controversial TR cells as key controllers of self-tolerance.
Transcription factors are key controllers of the signalling cascades activated during development.
The mapping of TFBS is important to infer the regulatory networks of transcription factors (TF) which are key controllers of gene expression.
The vascular endothelial growth factor (VEGF) cytokine family members are key controllers of angiogenesis and lymph angiogenesis [ 1].
