Sentence examples for the issue of differentiation from inspiring English sources

As classical chemotherapeutics only tend to highly proliferating cells and do not address at all the issue of differentiation arrest, a better understanding of these cytogenetic aberrations would facilitate the development of targeted therapies.

Whereas mechanisms controlling the differentiation of Th1 cells, Th17 cells, and regulatory T-cell subsets are well described, the issue of Th2 differentiation is still being debated.

The large eddy simulation of turbulent flows is discussed with particular attention paid to the issue of commutation of differentiation and filtering.

Woolcott said there were particular concerns about the longstanding issue of "differentiation" – the different requirements of rich and poor countries enshrined in the original 1992 climate convention which rich nations argue no longer reflect the world's economy or its greenhouse emissions.

In this work, the authors aim to seek a stream control solution and a transmission schedule with minimum frame length to satisfy traffic demands of links, and pay no attention to the issue of supporting service differentiation for different traffic sessions.

The issue of how genetic differentiation is maintained on such a small spatial is also unclear.

The issue of host use and genetic differentiation among populations also bears on the choice of potential biocontrol agents.

The issue of how to induce the differentiation of stem cells efficiently and keep the long-lasting function is still not addressed.

We here address the issue of the history of gene flow during differentiation in an original environment, hydrothermal vents in the deep ocean.

First, the issue of population structure (i.e. significant population differentiation) has been raised as one of the most likely causes of association between genetic diversity and fitness related traits.

However, the issue of whether increased TCR signal leads to Th2 differentiation remains very controversial.