Sentence examples similar to the isolated dose from inspiring English sources

There is very little evidence on the direct in vitro effects of these agents on cardiac contractile function in sepsis, and the isolated, dose-dependent effects of these induction agents on myocardial excitability, contractility, coronary flow, and oxygen utilization in a septic heart are still unknown.

Before dosing, animals were moved from the colony room to an isolated dosing room within the testing laboratory.

Elliott (2008a) drew attention to some difficulties of ignoring distinctions between isolated dosing points and intact dose response relationships.

Using a reliable bioassay system based on cAMP production in RXFP2-expressing HEK-293 cells, we were able to show that the isolated RLF/INSL3 stimulated dose-dependent cAMP production with an EC50 value of approximately 5 nM.

The isolated aggregates acted as dose-dependent nucleation templates ("on-pathway" aggregates), because the conversion of monomeric aSyn into amyloid was significantly enhanced as the SERF1a:aSyn ratio was increased, and the initial lag phase was visibly reduced.

A cangrelor infusion of 6 μg/kg/min is equivalent to a final blood concentration of 200 nmol/L, but we found no evidence of protection in the isolated heart over a dose-response range of 20 400 nmol/L (39±3%3 %, 41 ± 3 %, 36±3%3 % and 44 ± 5 % for control, 20, 200 and 400 nmol/L Cangrelor respectively, p = 0.5642, Fig.  1b).

Purified metabolites were subjected to disk diffusion antifungal assays with P. citrinum as the fungal test species at escalating doses of the isolated metabolites (0, 5, 10, 20 μg).

EAE induced a definite contraction of the longitudinal muscle in the isolated rat colon strip at a dose of 10−6 g/mL.

FDA induced in-vitro contraction of the isolated rat's uteri in a dose-dependent manner.

It has been demonstrated that H2S-donor compound, sodium hydrogen sulfide (NaHS), causes dose-dependent relaxations of the isolated rat aorta and mesenteric arteries.

The isolated compound significantly attenuated the abdominal constriction provoked by the acetic acid in a dose dependent manner.