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As very little is known about the role of mononuclear cells and their protein alterations in MDS the goal of this work, our aim, has been to describe the changes in the proteome of mononuclear blood cells of MDS patients and to discuss the involvement of these changes in MDS pathophysiology.
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However, the involvement of these tissues in OA and the changes produced by estrogen in related animal models suggest a potential role of estrogen in OA changes.
The involvement of neuronal changes in the central nervous system in the development of chronic pain was demonstrated across multiple studies.
Overall, the involvement of epigenetic changes in cancer is well studied, and the involvement of epigenetic changes in cancer initiation are discussed elsewhere [17,18,23,117,118].
A resting-state functional magnetic resonance imaging (fMRI) study examined the involvement of specific changes in cerebral network connectivity before and during PACAP38-induced migraine-like attacks in MO patients [44].
Although the involvement of epigenetic changes in FRDA etiology is undisputed, the exact extent of the epigenetic changes remains unclear.
Tonna et al propose the involvement of epigenetic changes especially for the development of diabetic nephropathy [ 20].
A number of indirect lines of evidence point to the involvement of epigenetic changes in diabetic nephropathy.
We evaluated the involvement of mitochondrial changes in αMHC-MerCreMer mice after injection of 3×60 μg tamoxifen/g body weight.
In conclusion, we demonstrated that DTI could detect the involvement of and changes in the CST in patients with medulla infarct during motor recovery.
Molecular studies during frog development were the first to provide strong evidence for the involvement of epigenetic changes in gene regulation by TR during vertebrate development.
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