Sentence examples for the initial two doses from inspiring English sources

In the recent TREAT trial, diabetic patients with CKD were at highest risk of mortality when they had a poor response to the initial two doses of darbepoietin alfa [ 6].

No additional dose escalation was carried out in the case of appearance of adverse events, lack of benefit with the initial two doses (no benefit on patient VAS), patient's satisfaction with pain relief, the highest dose was reached, or patient's noncompliance.

At the initial two dose levels, no DLTs were observed and the combination was well tolerated at cycle 1.

The initial three doses (0.5, 1, and 2 mg) were systematically administered at the beginning of the test.

The initial three doses were spaced two weeks apart, followed by 11 doses spaced four weeks apart, so that the treatment period lasted approximately one year.

As per the protocol, BM received after the initial five doses of chemotherapy, showed an abrupt reduction in the percentage of the above mentioned cell population.

Interleukin-2 was offered to all patients who had no tumour regression after the initial four doses of the vaccine alone, as concurrent treatment and to the patients who had recurrence following the adjuvant autologous vaccine.

A standardized dosing regimen (cumulative dose 10.4 g in the initial two weeks, maintenance dose 400 mg/day, five days per week) was used in eight patients with ventricular arrhythmias.

Most IRAEs occurred during induction (initial four doses given once every 3 weeks).

This was a retrospective, consecutive series of our initial clinical experience with patients' initial three doses of aflibercept.

The newly introduced dose decrement after the initial four high doses of IL-2 attenuated a counter-regulation encountered in an earlier regimen (Böhm et al, 2002).