As the mean volume administered into the allocated NLFs was virtually identical and the initial safety and efficacy of the two study products were very similar, a fair comparison of outcome for these two fillers is assumed.
To evaluate the initial safety and effectiveness of the intrauterine ball (IUB), a copper intrauterine device that, upon insertion in the uterus, takes a three-dimensional spherical form.
Currently, there are six cancer clinical trials underway using nanoparticle-based siRNA delivery, all in Phase I, evaluating the initial safety and utility of these treatments (Table 1).
In this phase I study, we demonstrate the initial safety, feasibility, and biologic plausibility of using H5.020CMV.PDGF-β H5.020CMV.PDGF-βleg ulcer disease.
To determine whether catheter-based near-infrared spectroscopy (NIRS) signals obtained with a novel catheter-based system from coronaries of patients are similar to those from autopsy specimens and to assess initial safety of NIRS device.
To determine whether catheter-based near-infrared spectroscopy (NIRS) signals obtained with a novel catheter-based system from coronaries of patients are similar to those from autopsy specimens and to assess initial safety of NIRS device.An intravascular NIRS system for detection of lipid core-containing plaques (LCP) has been validated in human coronary autopsy specimens.
Asterias Biotherapeutics announced the results of an initial safety study of the therapy earlier this month, and yesterday the company won $14.3 million from the California Institute for Regenerative Medicine (CIRM) for the next round of trials.
Following review of initial safety data of the candidate vaccines, Groups C and D were increased to 27 vaccine and 9 placebo recipients to better inform potential subsequent larger phase II studies.
The company has now sponsored an initial safety trial of the strategy in four infants with PMD.
Importantly, and unlike other AAV serotypes, for instance AAV-2/8 (Stieger et al, 2008), there was no transduction of AAV-2/9 along the optic nerve, which highlights an initial safety profile of this serotype.
