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A conversation ensues about the size of her name on a children's book she's written the foreword to: Donaldson felt her name had been too big on the initial proof, given she hadn't written it.
When it comes to funding, he describes money raised to-date as "relatively nominal" — with a government research grant from the Technology Strategy Board funding the initial proof of concept.
The initial proof, contained in [50], is valid for Alexandroff spaces.21 The generalization of the same result to arbitrary MMS satisfying (CD K,infty )) is done in [6].
They realize that the lack of standards and unproven manufacturing technologies makes it difficult for various producers to commit to the adoption of the initial proof of concepts that were available.64 The two concerns together led DuPont to organize a top level strategy meeting in Greece in 2010, to identify ways of moving forward.
It's the clinical discovery, and the initial proof that the gene is important for pain.
This study provides the initial proof of concept for p97 as a carrier capable of shuttling therapeutic levels of drugs from the blood to the brain for the treatment of neurological disorders, including classes of resident and metastatic brain tumors.
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The team tells TechCrunch that the initial proof-of-concept was built at PennApps Spring 2014.
In addition to showing equal potency against wild-type and multidrug resistant HIV-1, the AZT CSA conjugate displayed significant contraceptive activity in an animal model, providing the initial proof-of-concept for the design and synthesis of dual-activity compounds based on these combinations.
The rational and progressive development of tyrosine kinase inhibitors (TKIs) since the initial proof-of-concept studies with imatinib mesylate in the late 1990s, all designed to exploit key pathways that lead to GISTs being so oncogenically addicted, have revolutionized the treatment of GIST.
Noteworthy, the initial proofs of efficacy on immunotherapy in central nervous system metastases are already fostering clinical trials investigating its therapeutic potential also in primary brain tumors.
The initial proofs of Hunziker and van Winter relied on integral equations (what are now called the Weinberg van Winter equations).
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