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The initial clue to cancer of the vocal cords is often persistent hoarseness.
Gout was the presenting problem for 26, and asymptomatic hyperuricaemia was the initial clue for three.
Apical BK channel activation by forskolin and IBMX provided the initial clue that cAMP-dependent phosphorylation of BK channel protein (or an associated protein) might be an important regulatory step.
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Investigators said the initial clues pointed toward Boston, Canada and Florida.
Many of the investigators believe that some of the initial clues that were uncovered about the terrorists' identities and preparations, such as flight manuals, were meant to be found.
These prospective studies on the immunopathological characteristics of CRSwNP might provide the initial clues to link the inflammatory patterns of CRSwNP with concomitant morbidity.
The initial clues that modulation of sirtuin activity might affect AD pathology came from studies reporting that a sirtuin agonist, resveratrol, was able to attenuate cell death induced by Aβ and oxidized lipoproteins in cell culture models.
This finding implies that either common promoter elements or a feedback mechanism from the assembled complexes influences the levels of mRNAs Although the identification of the core promoters and their conserved TFBS of 98 OXPHOS genes provided the initial clues to understand this process, further work will be required to fully define the precise mechanisms responsible for this co-expression.
While read mapping provided the initial clues about HEs, the precise locations and boundaries of HEs across a set of lines were difficult to assess based on read mapping, thereby requiring a tedious validation procedure based on PCR and targeted sequencing in the study reported [ 27].
The company got its initial clue for the drug by making different genes in mice overactive.
A repeat reaction of tBu2Zn, nBuLi and the diamine in the additional presence of the bulky ketone (tBu 2C=O (Scheme 3) may have provided an initial clue to the mechanism behind the formation of 4.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com