Sentence examples for the initial checkpoint from inspiring English sources

The exposure of telomeric DNA does not affect the initial checkpoint response, but it allows for an accelerated recovery from the checkpoint arrest and resumption of cell cycle progression (Michelson et al. 2005).

Importantly, although the majority of TFP-co-treated U1810 cells subsequently overcame the initial checkpoint arrest, the percentage of TFP-co-treated TFP-co-treated TFP-co-treated abnormal mitosis incellsedisplayingantly after 48 hallmarks

Furthermore, for N between Nopt(M,L) and Nopt(M,L+1), it is optimal to choose the initial checkpoint C M,N) so that C M,N −1 and N− C M,N) fall between the values that they would have had to equal, if N had equaled Nopt(M,L) or Nopt(M,L+1).

Gene promoters and their cis-regulatory element composition, however, are the initial checkpoints for transcriptional gene activities and define the potential spatiotemporal expression of a gene.

Nearly forty-five minutes later we were released from this initial checkpoint with stickers in red on all our bags.

After passing through the jail's initial checkpoint (where a sign said: "Who is in the middle of SECURITY? UR!"), the actors gathered in the gym, rehearsing swordplay and doing vocal warm-ups to the amusement of some officers.

"The preliminary findings of our internal investigation have determined established protocols were not followed at an initial checkpoint, verifying that two individuals were on the guest list," Mr. Sullivan said.

We propose that close to the chromosome end (<5 kb) both Pif1- and Exo1-dependent activities generate ssDNA, causing weak initial checkpoint activation.

Phenothiazine-co-treated cells underwent prolonged initial checkpoint arrest followed by checkpoint escape, defective mitosis, dramatically increased ROS production and finally apoptosis associated with intense vacuolation and lysosomal expansion.

A comparison of DNA content analysis with CFSE dilution dynamics revealed that phenothiazine delayed but did not prevent bleomycin-treated U1810 cells from escaping the initial G2-M checkpoint, which occurred between 12 and 18 h post-treatment (as opposed to approximately 6 h post-treatment in the absence of phenothiazines).

Edwin M. Donovan, a spokesman for the Secret Service who spent his Thanksgiving Day dealing with phone calls from reporters, would not discuss the investigation in detail but said the initial focus was on "a Secret Service checkpoint which did not follow proper procedure to ensure these two individuals were on the invited guest list".