Exact(9)
Although we show that the down-regulated miR-20b leads to an increase in the levels of the anti-apoptotic factor, BcL-xL and a decrease in the levels of the pro-apoptotic factor, Bax, the informatics analysis indicate that neither BcL-xL nor Bax as a candidate target gene for miR-20b.
JAT and IJG carried out the informatics analysis.
To corroborate the informatics analysis, the peaks were manually visualized using the Integrative Genomics Viewer (IGV) genome browser [ 22].
DRM supervised the experiments completed by BCT, SPL, and MS, participated in the informatics analysis of FSTs, and edited the manuscript.
The informatics analysis is relatively easy, as any read that does not map to a locus between primers can be disregarded.
The informatics analysis revealed that the 'at risk' haplotype of the ESR1 promoter was predicted to alter transcription factor binding (Fig. 2, Table 6).
Similar(51)
The authors wish to thank Mel Andersen for his review of the manuscript, Linda Pluta for her assistance in the laboratory, and Longlong Yang for his help on the informatic analysis.
JLai participated in the informatic analysis of the FSTs.
The informatic analysis of spoligotyping results is carried out by Bionumerics program and is based in presence/absence or numerical analysis 1/0 of a specific sequence of M. tuberculosis.
Although this informatics analysis is a new trial to identify exon-level annotations, it is likely that insufficient researches has been performed on splicing isoforms.
The bio informatics analysis is suggestive of the role of the amino acid insertions in immune escape in the chronic phase of the HIV-1 infection.
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