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The second limitation was not grading ear lobe crease; recent evidence has pointed out to the relationship between the increasing grades of ELC and the increasing severity of coronary artery disease[ 16].
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The effect of the increasing grade of concrete is also presented.
Also, the intensity of staining in the cancerous cells was proportionally increased with the increasing grade of the lesions.
The higher p53 over expression with the increasing grade of GBC suggests its role in tumour progression rather than initiation.
This indicates that serum ALT levels could be used to point towards the increasing grade of liver inflammation.
However, the expression of hTERT levels was greater in invasive cervical cancer samples and showed an increasing trend with the increasing grade of dysplasia/cervical cancer.
Increasing over expression of p53 with the increasing grade of the tumour and decreasing over expression of c-erbB-2 with increasing grade suggest that c-erbB-2 is likely to play a lesser role in tumour progression in comparison to the p53 gene.
Our results confirm the higher prevalence of HPV infection in women with abnormal cytology, in concordance with most studies so far published, that have observed that the increase in HPV prevalence is related to the increasing grade of squamous intraepithelial lesions [ 22- 26].
It has been shown that astrocytomas are characterized by a general decrease of RNA editing mediated by ADAR2 enzyme [ 19- 26, 26] and that a correlation exists between the progressive loss of ADAR2 activity and the increasing grade of tumor, with the lowest editing levels found in AAs and GBMs [ 20].
A good correlation was always found of the increased grade of chondral degeneration and the grade of OA in standard radiographies.
Although the CDC6 mRNA increased with increasing grades of the clinicopathological classifications (except for the T-stage) of SCC, the Kruskal-Wallis test did not reveal statistically significant overall correlation of CDC6 mRNA level with tumor size (P = 0.159), lymph node status (p = 0.145), clinical stage (p = 0.242) or histological grade (p = 0.052).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com