To gain insight into the implications of sequencing error in phylogenomic applications, we performed a series of simple, descriptive analyses.
To explore the implications of sequencing information and stated preferences for return of results among research participants.
We also provide evidence that each FFRP has significantly functionally diverged at the protein sequence level, and in subsequent sections we will explore the implications of this sequence level divergence on the function of each FFRP.> -wrap-foot> Upper triangle contains pairwise coefficient of functional divergence (θij) between FFRP i and j and the standard error (SE).
We discuss the implications of these comparative sequence data for understanding the evolutionary history of primate PCSK9, hypotheses concerning their role in primate phenotypic evolution, and insights into PCSK9-associated human diseases.
As no structural information is available for A. rhizogenes OCD, the implications of its differing sequence are unclear.
The authors present a useful section on oncogenetic counselling and genotype/phenotype relationship discussing the implications of distinct BRCA1/2 sequence variants and disease association.
Finally, the future directions of the field are discussed with respect to using blood gene expression to tailor antipsychotic medications to individual patients, applying microRNA expression for diagnostic purposes, as well as the implications of next-generation sequencing technologies for gene expression analysis.
The PHG Foundation's 2011 review of the implications of whole genome sequencing states that increased involvement of minors in decision-making through assent is standard practice, and identifies re-consent at age of majority as an emerging practice [ 47].
Using the highly diverse pspC locus, we have now characterized the functional and immune implications of sequence diversity within the PspC protein.
While the implication of low sequence identity between the bacterial and Populus UGPase isoforms on enzyme activity is yet to be clarified, the functional activity of AxUGPase has shown to complement cellulose negative mutant phenotype by channeling sugar substrate for cellulose synthesis [ 34].> -wrap-foot> Data represent means ± SE (n ≥ 3).
