Current biologic therapies and the implementation of treat-to-target strategies make remission an affordable goal.
For example, recent studies on malaria and chagas diseases have shown that the decrease of vector densities observed after the implementation of insecticide treated nets coincided with the decrease of the antivector saliva IgG response, both at individual and community level [ 2426]6].
"It was the perfect field," I wrote, "the implementation of technology to treat a widespread problem like world hunger".
This is due in part to the implementation of 'Seek, Test and Treat' (now 'Seek, Test, Treat and Retain') initiatives which rely on the premise that scaling up treatment collectively will result in a dramatic reduction of HIV transmission (Montaner et al. 2010).
Furthermore, the availability of a high performance, rapid, and simple to use test would allow the implementation of a test and treat regimen, whereby patients are treated on site during the initial visit.
The implementation of anaerobic digestion to treat biowastes has become a grown-up technology.
We are particularly interested here in how community viral load creates or builds on existing personal allegiances and specific ties between individuals and communities to support the implementation of 'Seek, Test and Treat' initiatives (Miller and Rose 2008).
In such case, the implementation of traditional UCD by treating the imperfect CSI as perfect CSI cause significant performance degradation due to inevitable channel estimation error and vector quantization error.
The implementation of conventional pump-and-treat remediation for such DNAPL source zones has been ineffective in reducing contaminant concentrations to regulatory end points in acceptable time frames (MacDonald and Kavanaugh 1994; Travis and Doty 1990; U.S. EPA 1996).
Major challenges facing the implementation of the test-and-treat strategy relate primarily to the sheer numbers involved, creating even greater obstacles than those seen in current ART scale-up programs, as many people infected with HIV would qualify for ART. 15 Where health infrastructure is weak, it would need to be strengthened to cope with the increase in demand.
77 The implementation of the test-and-treat strategy will produce a rapid decline in HIV incidence and mortality and thus a shift in focus, from ensuring that everyone infected is placed on treatment to managing patient adherence and minimizing transmitted resistance.
