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This is a choice made to ensure specificity, and does not present a limitation when searching for TEI affecting phenotype as the impact of a nested TE insertion is likely minor compared to that of the already present TE.
If there's a major adverse event in the nested study, what does that mean for the host study?' (003, PI) The impact of a nested study would also depend on compatibility - the degree to which both studies used similar procedures and criteria.
Similar(58)
The aim of this research was to create and assess the impact of a new nest socialization program.
42 Challenges for host trials include increasing complexity and management burden, compatibility between host and nested study and the impact of the nested study on host trial design.
Funders may have concerns about the impact of the nested study on the progress of the host trial.
Challenges for host studies included increasing complexity and management burden; compatibility between the host and nested study; and the impact of the nested study on trial design and relationships with collaborators.
Both studies, however, differ from the one described in this manuscript as they adopted a different methodology, i.e. not a step-wedge approach, and focused on assessing the impact of a specific set of additional interventions nested within the insurance program, rather than assessing the impact of the insurance scheme per se.
Data for this longitudinal study is nested within a randomized controlled trial (RCT) assessing the impact of a 24-hour hotline and postpartum support film on postpartum stress.
And the impact of a no".
The impact of the nesting grid ratio (NGR) on the model performance needs systematic analysis and explored in the present study.
Finally, our design provided an opportunity to examine the extent of natal family influences on cognitive traits, as well as the impact of rearing nest.
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