Sentence examples for the immune privilege from inspiring English sources

The finely balanced anti-inflammatory microenvironment within the CNS contributes to the immune privilege status of this tissue.

In this context, they can protect against neuroinflammation by invading T cells contributing to the immune privilege of the CNS [117].

Despite the immune privilege of the central nervous system, and to a lesser extent the peripheral nervous system, immune dysregulation is not uncommon.

Factors that facilitate corneal gene delivery are the accessibility and transparency of the cornea, its stability ex vivo and the immune privilege of the eye.

The triggers of the vigorous immunologic and inflammatory responses against ocular antigens are poorly understood, and the mechanism by which the immune privilege is lost is yet to be fully described.

Fas expression might reinforce the immune privilege of apoptosis-resistant tumor cells, which, in most cases, express low levels of Fas and thus, cannot sufficiently respond to apoptotic signal brought about by FasL in immune cells (Nagata, 1999; Strasser et al., 2009; Zhou et al., 1998).

There is enough evidence which now suggests that MSCs are not inherently immune-evasive and the immune-privilege status is a flexible state depending upon cell to cell interactions and importantly soluble factors secreted by MSCs [35].

Breakdown of the immune-privilege status of the discs has been noted as an essential pathogenesis factor contributing to the IDD [ 29].

Not the inherent immune privilege of the CNS but the acquired immunosuppressive effect in glioma progression was the main cause of the suppressed FLNC antibody response in high-grade gliomas.

Thus, trophic factors networks in the adult CNS not only protects axons and myelin but appear to also actively contribute to the maintenance of the brain immune privilege.

In combination, these data suggest the basis for the relative immune privilege observed in ESC derived tissue after transplantation [2], [13].