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Massively parallel ('next generation') resequencing is potentially a powerful tool with which to study heteroplasmic mitochondrial DNA (mtDNA) mutations because of the possibility of the high breadth and depth of coverage.
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Alongside the higher breadth, the increased magnitude of responses found in LTNPs by ELISpot assay was confirmed by ICS analysis, although not reaching statistical significance, when we determined the percentage of IFN-γ-, TNF-α and IL-2-producing CD8+ T-cells following stimulation with specific peptides (Figure 3A).
As we can see, the triangle is essentially consisting of problems inherent in any double bottom line or hybrid entity: how to balance the need for high breadth of outreach and economic profitability with the need to reach the most vulnerable and have an impact in getting them out of poverty by helping them develop their enterprises.
The entries of column E of Table 1 show that the RSCU' of most codons is either positively or negatively correlated with breadth of expression, indicating that indeed the high codon bias in the genes with low breadth of expression results from preference for different codons than in the genes with high breadth of expression.
The 3D menu was preferred by users at high breadth levels, and the 2D menu showed better performance than the 3D menu with low memory load.
Table 2 Wild Card assessment main (concise) results from the expert survey Wild Card Impact * = Low ** = Medium *** = High Breadth of effect Main Vulnerability Importance for decision makers Main weak signals Aviation Road Rail 1 1.
These patterns form "cascades" with different profiles: for instance, a fast-spreading rumor that's quickly snuffed out would have high breadth but little depth, and low virality.
Goats and dzomos showed the highest diet breadth value (0.73) followed by sheep (0.53) and cows or donkeys (0.44).
Negative values, on the contrary, are related to phalanges with a flat appearance due to high breadths at midshaft and at the distal end (i.e. with apical tuberosities instead of tufts).
The primary advantages of cohort studies are the high quality and breadth of data that can be generated.
For one immunogen, the neutralizing response was increased with a higher breadth compared to the Wild-Type.
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