Exact(2)
However, due to the small cohort and the high between subject-variability, only the density in the subiculum molecular layer yielded a significant group effect.
The 90% CIs for the Arm A/Arm B ratio of geometric means of Cmax, AUC0-t, AUC0-inf, and AUC0-tau are given in Table 3; these CIs were not wholly contained within the 0.6667 1.500 range, largely because of the high between subject variability associated with the artesunate pharmacokinetic parameters.
Similar(58)
The high between-study heterogeneity and the sensitivity analyses suggested that the second estimate was more reliable.
The high between-trial variability in the drift parameter is the dominant source of variability affecting the choice outcome, so that the outcome is relatively immune to the location of the bound.
The lack of statistical significance for the effect of country, professional position and other sample characteristics is not strong evidence against their relevance, because the high between-study variance caused by methodological factors limited the power of the analysis (the regression had to control for three methodological factors before testing any other effect).
The high between-subject versus within-subject R ratio (0.51/0.07) is worth noting.
Perhaps of greater concern is the high between-VISN variability of concordance, ranging from 36%to85%5%.
Such a pattern of dispersal could explain both the low within-population diversity and the high between-population differentiation.
Currently, these drugs are typically dosed as a fixed regimen (dose amount and frequency) across all patients despite the high between-patient variability in pharmacokinetics (PK).
Although a recent meta-analysis revealed an effect size of 1.17 for reduced volume of the left anterior cingulate in bipolar patients relative to controls, this finding was not significant across studies due to the high between-study heterogeneity [ 2].
Furthermore, an increasing number of latent groups results in greater between sample SD, reflecting the greater population diversity, but the effect is more moderate in the high between-to-within SD scenario (U).
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