The primary objective is to determine the effectiveness of a systematic osteoporosis screening and treatment program on the hazard of developing a fracture over the treatment period.
The hazard of developing a breast or ovarian cancer hbo(x) is therefore a mortality hazard.
These risk factors translate into a substantially increased risk of morbidity and mortality; for example the hazard of developing a myocardial infarct in early-onset T2DM (< 45 years) is 4-fold higher than in late onset T2DM (> 45 years) and 14-fold higher than in people without T2DM [ 6].
Mrs. Merkel has used her influence to open doors and help companies deal with the hazards of developing markets, which remain much riskier than Europe.
To facilitate interpretation of results, the hazard ratios for the piecewise linear spline variable (fluoroquinolone exposure while on CDI treatment) compared the hazards of developing CDI for values between the 75th and the 25th percentiles of the variable [ 20].
Data from the 10%- and 90%-trajectories were used to estimate age-dependent per-cycle hazards of developing a carious surface in low- and high-risk individuals, respectively.
We therefore defined hbo(x) as the hazard associated with the risk of developing a non-sporadic breast or ovarian cancer.
Figure 1b illustrates the four separate time-specific recurrence hazards and shows that the risk of developing a first relapse event is fairly stable across time since surgery.
Based on the width of the confidence intervals presented in Table 3, we can exclude (with 95% confidence) a >24% increase in the hazard of developing CHF and a >51% increase in the hazard of developing CVD per 1 SD increase in sex-standardized log-leptin in models assessing incremental contribution of leptin levels over BMI.
The West of Scotland Coronary Prevention Study reported a 30% reduction in the hazard of developing diabetes with pravastatin.
