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The size of the population with general MCI limits the generalized use of biomarkers or therapies and shows the need for more specificity in identification of the target population.
Currently, major progress in tumor characterization comes from the generalized use of global genomic and postgenomic analyses (next-generation sequencing, transcriptomics, proteomics).
In some cultures the generalized use of surnames did not occur until the 20th century: in 1935 a Turkish law went into effect making surnames mandatory.
In case of distribution systems, a vast improvement of power quality phenomena is envisioned owing to the generalized use of power electronic devices [76, 77].
However, the generalized use of more complex numerical models for the back- and forward-analyses of real events still remains limited, since information on individual sites and the characteristics of events are usually limited.
Because there is no evidence for outcome benefit and because data on renal toxicity are conflicting, recent guidelines from the Infectious Diseases Society of America (IDSA) concerning the treatment of methicillin-resistant Staphylococcus aureus (MRSA) do not support the generalized use of a continuous infusion for vancomycin in these circumstances [81].
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A model of within-plant carbon allocation is proposed which makes a generalized use of the Münch mechanism to integrate carbon and water functions and their involvement in growth limitations.
Undoubtedly, the greatest efforts should be directed toward improving screening campaigns as the most effective means for reducing cervical cancer mortality; however, while this is being achieved generalized use of the most effective therapies for invasive cancers may contribute to decrease in mortality.
The systems of calculating care load have not yet reached the levels of generalized use which the systems of prognostic estimation of survival have.
For network meta-analysis of standardized mean differences (SMD), a frequentist method was applied using the R package netmeta [ http://www.r-project.org/] [ 27, 28], using the generalized method-of-moments estimator of between-study heterogeneity given in [ 29].
In the last decade, the use of generalized additive models (GAM), which allow non-parametric smooth functions to control for possible confounders, was a standard approach on air pollution time series analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com