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The general specificity information is obtained from the arrays is expressed in a regular expression form.
Nevertheless, the general specificity of these compounds is not established and off target effects that exist are likely reduced by considering acute treatments.
Repeat experiments with cRNA containing modified ATP supported the general specificity trend: unmodified ATP > 1 1 DAP A > all DAP (data not shown).
These factors were chosen because they represented qualitative descriptions of the general specificity or nonspecificity of chemicals with regard to the activity in rodents and have some bearing on the potential activity of chemicals in humans.
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In this study, we evaluated the magnitude, general specificity and character of HIV specific CD8+ T cell responses at four time points across 2-9 years in 2 groups of chronically infected individuals separated on the basis of either effective antiretroviral suppression or ongoing replication of HIV.
In our study, where initial samples were drawn at least 3 months after establishment of viral suppression or viral replication, the absolute magnitude, general specificity and subset distribution of the CD8+ anti-HIV T cell response remained remarkably constant.
Magnitude, general specificity and character of the HIV-specific CD8+ T cell response changed little over the study period.
The general taxon specificity of scaffolds was confirmed by the fact that less than 0.8% of all scaffolds were homologous to both the Tc and Dp genomes.
The tests were further compared with regard to general specificity, particularly cross-reactivity with rheumatoid factor, speed, simplicity, their ability to detect other species, storage requirements and general presentation.
Among the investigated antibody fragments we found three scFvs exhibiting a general specificity towards β-amyloid while two scFvs, PaD213-A5 and PaD233-E5, presented a tendency to better bind to certain forms of Aβ42.
The fractional contribution of each individual HIV protein to overall magnitude indicated general specificity.
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