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Sequencing of the FUS gene revealed no pathogenic FUS mutations in these five cases.
Cytoplasmic inclusions of fused in sarcoma (FUS) are the hallmark of several forms of FTLD and ALS patients with mutations in the FUS gene.
BBB-opening and drug delivery were achieved concurrently during the FUS exposure.
Questions on key outcomes in the FUS are identical to those in the baseline survey (FBS).
The FUS collects information on the same youth interviewed in the baseline survey (both treatments and controls).
None of the FUS patients was on active medications as, for example, local corticosteroids at the time of examination.
Similar(11)
The expression of the FUS-DDIT3 transgene in liposarcomas was assessed by RT-PCR (Figure 1D).
Suppression of the FUS-DDIT3 transgene did rescue this adipocyte differentiation block.
These results demonstrate that tumors arisen in the FUS-DDIT3 transgenic mouse mimic human liposarcomas both histologically and molecularly.
Insertion of the FUS-DDIT3 gene under the control of the tetO-minimal promoter yielded the plasmid CombitTA-FUS-DDIT3 and mice were generated.
This could be unexpected, but the C/EBPβ activity has been shown to be important in the FUS-DDIT3-mediated interleukin-6 expression [44].
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