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Also this approach allows more design variables to be assigned in the further optimisation analysis.
The further optimisation of the novel lead compound CGH752 (Fig. 1) is described.
A moderate yield of pure AtGA3OX4 requires the further optimisation of the latter stages of the enzyme purification schedule.
The hit compounds reported herein represent starting points for the further optimisation of dual EZH2/EHMT2 inhibitors.
The further optimisation of the previously reported compounds 3 and 4 lead to a potent inhibitor with approximately a threefold improvement in activity.
We argue here that the optimum use of such a technique in clinical studies requires the further optimisation and standardisation of reporting procedures coupled with carefully planned prospective studies.
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In the development of a S-1/docetaxel combination therapy in the United States and Europe, further optimisation of the dose of each agent may be required to account for these differences.
The understanding of the physics of the coolant flow inside the device may hold the key to further optimisation of engineering designs.
The results have highlighted the significant contribution of plasma treatment to the overall environmental impact of the ML film and the need for further optimisation.
This is the slowest portion of the algorithm since each scoring method has to read and process the complete MSA (further optimisation, including parallelisation, will be addressed to this step in the near future).
Considerable differences remain between hospitals for the most frequently used CT protocols, indicating the need for further optimisation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com