Beyond the establishment of VH interactomes and the discovery of specific and common cellular functions targeted by viruses, studies have revealed the fundamental principles that have evolved by which viruses manipulate the cellular network [ 5, 10, 59, 60].
"Until recently, however, cognitive scientists have not paid sufficient attention to the fundamental fact that cognitive traits evolved under particular natural settings.
In 2016, the clock has been set at 3 minutes to midnight as tensions between the U.S., Russia, North Korea and other nations, particularly those involved in conflicts in the Middle East, remain high and landmark climate change agreements have not yet evolved into the fundamental changes needed to ultimately arrest the problem and mitigate additional conflict and catastrophe.
Recent studies have documented genome-wide patterns of divergence between closely related sister taxa (Ellegren et al., 2012; Kulathinal et al., 2009; Lawniczak et al., 2010; Nadeau et al., 2013; Neafsey et al., 2010; Staubach et al., 2012; Turner et al., 2005), but the fundamental question of how divergence evolves throughout the process of speciation remains largely unexplored.
While the music has evolved and outfits have evolved since the '60s, the fundamental duty of a go-go dancer remains the same as it has been for decades: to hype up a crowd -- especially one that isn't dancing.
The ability to probe systems like the nervous system at the fundamental resolution that they have naturally evolved to function is revolutionary.
Julian Huxley, a founding father of ethology, had the fundamental insight that behavioral displays often evolve in one context, then change function later in evolution.
And yet, even granting that one's views evolve over time, the fundamental question remains the same: Is requiring people to buy insurance -- which Heritage once championed and now opposes -- an illegal act?
I have worked on many different problems, all of them fascinating and deeply involving, but none, so far, have evolved to acquire the fundamental importance of my early adventures with symmetry breaking and mass.
Under this scenario the endomembrane system can be explained as an exocytic pathway because it evolved to export the fundamental components of the plasma membrane that can no longer be synthesized in this original compartment.
