Exact(6)
Different scoring functions were defined for scoring the conservation of residues in the functional positions based on their occurrence, probability of occurrence and by consulting the Dayhoff matrix.
Ye et al. proposed a two-entropy analysis to determine the functional positions in the transmembrane regions of GPCRs [41].
Cβ Cβ distances of the residues at the functional positions were calculated from the models of 131 classic OBP sequences (data not shown).
The functional positions of the core promoter elements as well as the distances between elements in synergetic combinations are the same for Drosophila and Human promoters.
We found that the region from position 3 to position 9 has higher F-score, which may be the functional positions in Drosha process.
The functional positions were adopted in a similar manner to the functional sites described by Skolnick et al 29 125 annotated query sequences from all 3 subfamilies (derived from SWISSPROT) were aligned to each of the subfamily profiles and the scores were checked for every query sequence against each profile.
Similar(2)
Our analysis suggests that thermophilic and hyperthermophilic photolyases have evolved structurally to preserve the functional position (and thus the catalytic function) of adenine at their high temperatures of operation.
Most post-operative adverse events may be attributed to malposition of the component in the functional position.
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