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Two models have been discussed to explain memory deficits after ATLR: the hippocampal reserve theory suggests that it is the capacity of the contralateral hippocampus which preserves postoperative memory function whereas the functional adequacy model suggests the functional reserve of the ipsilateral hippocampus as the key structure to support memory function after surgery (Chelune et al., 1991).
This finding is consistent with the functional adequacy model of hippocampal function.
The conclusion that memory function in unilateral TLE is better when sustained by the activation within the damaged hippocampus adds further support to the functional adequacy model of hippocampal function.
The functional adequacy model on the other hand suggests that it is the capacity of the ipsilateral hippocampus, which is to be resected, that determines whether changes in memory function will be observed.
Our results support the functional adequacy theory, suggesting that it is the capacity of the ipsilateral hippocampus, most likely the remaining posterior part, which preserves verbal and visual memory encoding function after ATLR.
The present study supports the functional adequacy model, in concordance with other neuropsychological and functional imaging studies, in particular for verbal memory (Baxendale et al., 2000; Bonelli et al., 2010; Helmstaedter et al., 2011 a, b ).
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Two different models of hippocampal function have been proposed to explain memory deficits following ATLR; hippocampal reserve and functional adequacy (Chelune, 1995).
The convoy model proposes that the structural, functional and adequacy aspects of social support is influenced by a person's traits and demands of the context; yet to our knowledge these assumptions, particularly in relation to recovery from MSI are yet to be established in the research literature.
The adequacy of the developed surrogate model to approximate the functional form of the first fundamental frequency is verified through various statistical and experimental methods.
The adequacy of the Cox proportional-hazard analysis was tested by checking the functional form and the assumption of proportional hazards as described by Lin, Wei, and Ying (Lin et al., 1993).
The functional and the dysfunctional.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com