Exact(7)
The function of the core sequence ACGT, present in a family of commonly occurring cis acting transcription regulatory motifs was investigated in the background of an artificially designed synthetic promoter sequence.
These oscillations in spontaneous firing rate (SFR) continue even in the absence of light input to the pacemaker [9], when time-keeping relies on the function of the core clock genes [1].
The function of the core proteins has been best studied in the Drosophila wing.
As a consequence, it is difficult in most instances to predict how these additional genes contribute to the function of the core SigB stress response.
This is despite the assumption that the function of the core PCP module in vertebrates may differ from the mechanisms acting in the Drosophila melanogaster epithelium.
DOI: http://dx.doi.org/10.7554/eLife.03502.007 10.7554/eLiFigure02.008 Figure 3 figure supplement 1. Decreasing the function of the core components of the SET1/MLL complex leads to a reduction in type II neuroblasts.
Similar(53)
The functions of the core and flexible CDS encoded on the various LPP-1 plasmids were determined on the basis of sequence similarity to characterized proteins.
A closer look at the functions of the core domains reveals that these domains possess rather "universal" functions and play biochemical roles in a broad range of biological processes.
These results thus indicate that BCR/ABL does not interfere with the function of the FA core complex, required for FANCD2 monoubiquitination, but rather with downstream steps in the FA pathway.
Pladienolide, spliceostatin and herboxidiene modulate the function of the spliceosome by binding to the SF3B core component protein [ 49, 50].
RNA-binding function of Hfq mainly lies within its N-terminal core, whereas the function of the flexible domain remains controversial and largely unknown.
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