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Exact(5)
The frequency of mismatches and gaps in the alignment between contig sequences and the reference genome was determined by BLAST.
For example, the frequency of mismatches and gaps in the alignment between contig sequences and the reference genome dropped significantly (p<0.01) from 0.24 mismatches/kbp and 0.70 gaps/kbp in the 454-only assembly, to 0.19 mismatches/kbp and 0.44 gaps/kbp in the hybrid assembly.
In most organisms there are evolutionarily conserved mechanisms in place that minimise the frequency of mismatches introduced during DNA replication [ 1].
This may explain why ACS and K r work well on closely related sequences, while kmacs is superior on distantly related sequences where the frequency of indels may be a better measure for evolutionary distances than the frequency of mismatches.
Thus, the average length of the longest k-mismatch common substrings depends on the frequency of mismatches and could be used to estimate substitution probabilities, just as in K r.
Similar(55)
Through these quality assessment exercises, we identified common causes for mismatched patterns and determined the frequency of mismatch occurrences among the laboratories.
The aim of this study is to determine the frequency of mismatch repair (MMR) inactivation in ovarian cancer and whether it is associated with platinum-based chemotherapy resistance.
The aim of this study is to determine the frequency of mismatch repair (MMR) inactivation in ovarian cancer and its association with resistance to platinum-based chemotherapy.
We hypothesise that this may be related to the frequency of mismatch repair-deficient tumours in this study, which may be greater than the expected.
Therefore the frequencies of mismatches due to sequencing errors are expected to be comparable across ESTs for the same genes.
For match states this ratio is 1, whereas for mismatch states it is the frequency of the specific mismatch dinucleotide in the 16-state model divided by the sum of the frequencies of mismatch states.
Related(20)
the frequency of dislocations
the frequency of disturbances
the frequency of asymmetries
the rate of mismatches
the degree of mismatches
the incidence of mismatches
the frequency of discrepancies
the frequency of inaccuracies
the frequencies of mismatches
the fraction of mismatches
the possibility of mismatches
the importance of mismatches
the kind of mismatches
the introduction of mismatches
the agency of mismatches
the extent of mismatches
the number of mismatches
the effect of mismatches
the frequency of words
the role of mismatches
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