A Monte Carlo test of 10,000 trials was conducted to determine the probability that the frequencies of migration events between each pair of localities in the original migration tree were more than expected when the localities were randomly distributed across the tree's tips.
In APC Min/+ tissue, the frequency of forward migration events is the same as in wild type (P=0.25) and enterocytes remained motile, with 0.29 migration events per hour towards the villus tip.
All malaria cases were imported from 2012 to 2014, the number of cases was mostly related to the frequency of population migration.
While it is difficult to determine the frequency of abnormal migration phenotypes in the live-imaging analyses, we assume that cells with positional defects observed in Fig 4C, 5A, 6B and 7A represent snapshots at the respective time points during normal or abnormal migration.
The variance among these 100 synthetic loci is thus due to variability in the frequency of certain migration events in each projection, which result in the presence or absence of certain alleles in each population at the end of the simulation.
Moreover, since the virtual machine migration operations consume additional energy, the frequency of VM migrations needs to be limited and controlled as well.
Therefore, despite that there are many complex and changeable reasons for electrical center migration in actual grid fault, the voltage frequency of migration satisfies the following rules all the time, namely, during the migration of the electrical center, the bus frequency at one side of electrical center circuit branch starts to have similar changes to the other side.
We carried out this numerical test 50,000 times and investigated the frequency of false migrations.
The frequencies of migrated CD19+ B cells and their CD27- naïve and CD27+ memory subpopulations are summarized in Figure 3A (baseline migration) and Figure 3B (net migration as the difference of actual minus baseline migration).
