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Additional support, in the form of replication using other despotic species and comparisons with less despotic macaques, is needed.
On the other hand, genome sequence differences have been examined by the copy number variation analysis between normal cells within a single organism [ 13- 15], which informed us of frequent occurrence of mutation in the form of replication slippage at particular genomic loci.
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These cells harbor HIV in the form of replication-competent proviruses that are integrated into the host genome.
"The result of this form of replication across cities is the wholesale denial of the very idea of locality," says Picardi. "Regenerated areas become separate, exclusive enclaves no longer interwoven with the city fabric and local built environment.
Resistance to VDA drugs such as KP1461, should it occur, may take the form of increased replication fidelity, which should result in a decrease in overall diversity and lead to propagation of less fit virus that is also less able to evolve resistance against standard antiretrovirals [25], [33].
Viral genes in the form of dsRNA generate during replication, which is the basis of using RNAi technology for its control.
The Introduction section summarised various approaches to this type of research, ending with the suggestion that a rigorous form of replication analysis is to develop a statistical model with one set of data and attempt to replicate it with another set of data.
Owing to such differences and other methodological variations, the possibility to implement this rigorous form of replication analysis is quite limited.
Our screen, by virtue of incorporating multiple concentrations of oligomycin and examining the trend of response, contains an intrinsic form of replication.
It should be added that the steps involving the duplication of DNA do not occur spontaneously; they require catalysts in the form of enzymes that promote the replication process.
Under stationarity, observations of a single realization of the random function at different positions can be treated as a form of replication.
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