He made the definition and adoption of a new system recognizable for others, made its acceptance an obligatory passage point for entering the network, and he became indispensable in the process, playing a focal role.
Our findings indicate that RAP plays a focal role in the biology of amyloid deposition either by regulating the maturation of proteins that modulate APP processing and Aβ metabolism, or by directly modulating other yet to be defined aspects of amyloidogenesis.
In mouse embryos, derivatives of the trophoblast lineage play a focal role in PGC specification (Fig. 1A).
Recent advances in DNA sequencing technology and their focal role in Genome Wide Association Studies GWASS) have rekindled a growing interest in the whole-genome sequence assembly (WGSA) problem, thereby, inundating the field with a plethora of new formalizations, algorithms, heuristics and implementations.
Mr. McMullan has played a focal role in all this, becoming an ally of his subjects and a starmaker.
Frankovsky is a Facebook vice president in hardware design and supply operations who plays a focal role at Open Compute.
The Spartans, who have been moved up to Division III, only lost four seniors, but the crop of Katherine Sheehy, Megan Reilly, Rose Quezada and Emma Tapp were all valuable contributors with plenty of experience, including playing focal roles in the Spartans' run to a Rio Hondo League title and a Division V championship appearance in 2014.
The real problem with State Fair -- in which the home-spun Frake family spends three days at the Iowa State Fair winning prizes for mincemeat and a pig -- is that it was miscast in its four focal roles.
For the focal individuals mating roles were noted and egg masses produced during both day (immediately upon laying) and night (next morning) were collected for egg counting.
Hence, controlling the optical field characteristics within the focal volume plays a critical role in determining the function and performance of these optical systems.
