Exact(10)
Discrepancies between the impact of OATP1B1 c.521T>C sequence variation between clinical studies and between clinical and in vitro data may reflect limitations of the fitting approach, which fixed parameter values for all but the fitted parameter and used average clinical data from a small study.
The fitting approach is also supported by the fact that the brake cylinder pressure is a widely measured parameter in both field and laboratory tests, so the accessibility to source data and their comprehensiveness are good.
The comparison and validation against the fitting approach commonly used in GRACE literature shows a very good agreement for what concerns trends and periodic signals on one side, and on the other it reveals where other behaviours can occur.
One objective of the fitting approach was to obtain an unbiased measure of the dispersion of the parameter estimates.
Another objective of the fitting approach was to avoid the bias in slope estimates that is introduced by conventional across-session averaging.
Since the fitting approach used in our study is concerned only with the 'visible' portion of the SAD it is not expected that this truncation should impact our ability to recapitulate community SAD.
Similar(49)
Although the LAS is getting acceptance, the mathematical fitting approach is very complicated and require advanced curve fitting and analysis procedure.
We found that the 'curve fitting' approach also used in the Humlum paper is another common theme in contrarian climate research.
Linear regression analysis was found to show high correlation (R 2 = 0.9927) and revealed values for k on of 8.859 × 107 ± 0.299 × 107 M−1 min−1 and for k offof 0.049 ± 0.006 min−1, which are in good agreement with the rate constants obtained from the global fitting approach.
As described previously, in the MPL fitting approach adopted in this paper, the path loss exponent is constrained to the value corresponding to the reference channel, i.e. the generalised static CP-LoS channel.
The charge parameter derivation was performed using the RESP fitting approach.
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