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The first substantial battle was reported in early August.
It was the first substantial protest in Deir Ezzor.
In January, Super Bowl XXXV in Tampa, Fla., provided the first substantial test of the software.
Mr. Bloomberg made the push for nonpartisan elections the first substantial proposal of his campaign.
This will be the first substantial show of Judd in this country.
It is the first substantial drop in breast cancer incidence in more than a quarter century.
The first substantial cultiviation there was begun in 1946 by a group of 20 French families.
In the next half-hour, we should see the first substantial numbers come in.
One of their governors, Étienne de Flacourt, wrote the first substantial description of the island.
The first substantial problem drama by Bjørnson was En fallit (1875; The Bankrupt).
It was introduced in 2004 and this year's harvest, the first substantial one, runs through the third week in September.
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