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In the first instance, I'd have health care reform.
In the first instance—I thought the relationship was straightforward, but it was not.
"It's the first instance I know of people selling work under my name," he says.
"It's not the first instance I've heard of this happening," he said.
In the second instance I visited my doctor.
In the first instance, these experiments confirmed the importance of thalamo-cortical innervation for the appropriate formation of cytoarchitectonic boundaries.
The first instance of "I'm obsessed" shows up in the New York Times archive in 1967.
I took this concept a little too far the first time I experimented away from home.
Using the notation of our model, the calculations address, in the first instance, the expenditure of insurers (∑ i =1 n D i w i ) and not consumer welfare (PW − S∑ i =1 n D i w i ).
In the first instance, this proof-of-principle experiment demonstrated that removal of Cys77 and Cys263 did not disrupt to any great extent the folding and secretion of wild-type matrilin-3.
This complexity had been a point of criticism during external peer review of the proposed study protocol, but we felt that each condition was necessary in the first instance and a simpler design was planned for experiment 2. For experiment 1 there were 8 possible trial types as defined by the first cue (rule cue).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com